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GLP-1 RAs under development for NASH Semaglutide Semaglutide showed a significant dose-dependent NASH resolution without worsening of fibrosis in a phase 2 randomized controlled trial (RCT) involving patients with NASH and stage 13 fibrosis

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This makes adhering to the treatment plan simpler and increases the compliance of patients who are taking care of their diabetes, providing a sustained therapeutic effect with fewer doses