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Plan sponsors may refuse to cover DTC prescriptions, which means patients will have to cover the full price of the medication, experiencing higher out-of-pocket costs and limiting access for those who need these medications the most

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However, a study found that taking 1,000 mcg of B12 by mouth or injecting the vitamin achieved similar results in treating the deficiencies

Another study found that GLP-1R activation in Brunners glands upregulated barrier defense genes, an effect entirely absent in GLP-1R knockout mice (53)

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