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Oxidative stress induced by NOX2 contributes to neuropathic pain via plasma membrane translocation of PKC in rat dorsal root ganglion neurons

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Alveolar macrophages derived from circulating monocytes recruited into the lungs by monocyte chemotactic factors produced by lung cells are increased 20-fold in COPD patients and release ROS as superoxide anions and hydrogen peroxide (102)

Because the induction of these genes is only transient, the glutamate consumption is likely to be buffered by steady-state central carbon metabolism, under which glucose and glutamate fuel mitochondria to support cellular bioenergetic demands (Fig

metformin: Although BSE did not meet the primary endpoint, its 0.2 mmol/L reduction in fasting glucose was comparable to metformin's effect in some diabetes prevention trials, with fewer side effects