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In the 1990s and 2000s, further non-RCT studies in the elderly with or without dementia/AD and low B12 status have also mostly shown no benefit of B12 for cognitive function

Autophagy and its role in maintaining mitochondrial health

[2] However, elevated MMA is not conclusive, as it is seen in people with B 12 deficiency, but also in elderly people who have renal insufficiency, [28] and elevated homocysteine is not conclusive, as it is also seen in people with folate deficiency

Furthermore, the nutrient is crucial during pregnancy to reduce the risk of birth defects of the brain or spine as well

Reconstituted Storage 28C, use within 2830 days