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Prolonged exposure to stress further elevates the activity of monoamine oxidase-A (MAO-A) while concurrently diminishing monoamine biosynthesis, thereby exacerbating depressive-like manifestations (26)

If you reach 2.4mg maintenance, it lasts about 4 weeks

Brenner M, Hearing VJ (2008) The protective role of melanin against UV damage in human skin

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(1) Overview Melanotan 1 appears to mimic the function of the endogenous -MSH and may bind to the melanocortin receptors to stimulate the production of eumelanin, a photoprotective compound