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That interpretation of the rules is being challenged in the courts by Novo Nordisk and Eli Lilly, which makes rival weight-loss therapy tirzepatide, while the compounders have countersued, claiming that the FDA's removal of the drugs from the shortages list was premature

Euro J Pharmac Sci

Tirzepatide is technically a dual GIP and GLP-1 receptor agonist, but many patients group it with GLP-1 weight-loss injections because it affects the GLP-1 pathway

Among these patients, 982 were treated by applying GLP-1RAs or DPP-4 inhibitors, while 2,769 received other antidiabetic medications

This situation has become more common as regulatory oversight tightens around compounded weight loss medications