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Characterising the genetic architecture of changes in adiposity during adulthood using electronic health records
A post-hoc analysis of SURMOUNT-5 estimated a larger reduction in predicted 10-year cardiovascular risk with tirzepatide (23.7%) than semaglutide (13.6%), but these are modeled projections, not measured outcomes
This includes limiting red meat, eggs, cruciferous vegetables, and high-protein processed foods Eat smaller, more frequent meals rather than large portions, which can overwhelm the already-slowed digestive system Avoid high-fat and fried foods that further delay gastric emptying Stay well-hydrated throughout the day to support digestive function Limit carbonated beverages which can increase burping and bloating Identify personal trigger foods by keeping a food diary to track which items precede sulphur burps Eating habits and timing also play important roles: Eat slowly and chew thoroughly to reduce the amount of air swallowed and improve initial digestion Avoid lying down immediately after meals
Starting at 4mg or higher "to save time" is the fastest way to end up nauseated, dehydrated, and questioning why you switched in the first place
Tirzepatide should be discontinued before actively trying to conceive, typically at least 2 months prior
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