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These findings suggest that restoring 133p53 expression or inhibiting serpinA3N may serve as potential therapeutic targets of senescence astrocytes in neurodegeneration

In addition to their role in promoting breast cancer cell proliferation [67] and mediating inflammation [68], breast CAFs deposit collagen type I and fibronectin [58], secrete matrix metalloproteinases (MMPs) [69], and promote collagen crosslinking (e.g., via lysyl oxidase (LOX)) [70]

Hsing AW

Detoxification: It plays a vital role in detoxifying harmful substances in the liver, aiding in the elimination of toxins and heavy metals from the body

Molecular mechanisms of the acute kidney injury to chronic kidney disease transition: an updated view