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Methoxymine (alpha agonist) combined with propranolol: regulation of portal hypertension hemodynamics A separate study involving 26 patients with portal hypertension and cirrhosis showed that the -agonist methoxamine and the -blocker propranolol reduced liver blood flow and splenic vein blood flow through different mechanisms, respectively 77

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[65] Hypotension, including orthostatic hypotension, may occur during treatment with hydrochlorothiazide and can be exacerbated by concurrent use of alcohol, narcotics, or antihypertensive drugs