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39 Given recent loss of exclusivity for key revenue generating therapies, Bristol Myers Squibb has focused on driving growth via recent drug launches and bolt-on acquisitions

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Also, autaptic hippocampal cultures produced from these transgenic mice showed a decrease in both amplitude and frequency of EPSCs, whilst neurons of Mecp2 Tg1 mice, with an upregulated Mecp2 gene, had an opposite effect [377]

Kalvelyte A, Imbrasaite A, Bukauskiene A, Verselis VK, Bukauskas FF

reported that RAS promotes glutamine metabolism, highlighting the importance of assessing co-mutations with PIK3CA mutations in future research 61