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10.1146/annurev.cellbio.20.012103.135836

In the STEP-1 trial, DEXA scans showed that lean body mass (muscle and bone) accounted for nearly 40 percent of the weight lost

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Taken together, these data demonstrate that cancer cells capable of enduring 5FU treatment have significant, sustained mitochondrial adaptations, driving enhanced mitochondrial biogenesis and fusion in the absence of evident mitochondrial dysfunction

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