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Conjugation can be either enzymic or non-enzymatic, nevertheless, GSH transferases are widespread in both animals and plants, and enzymatic conjugation is assumed to be particularly effective and may even result in GSH depletion

For subfamily AhpC-PRX1, we searched for the motifs GGLG and YF that encode sensitivity to hyperoxidation, as well as a and b motifs that contribute to determining the degree of PRX sensitivity to hyperoxidation 56,57,58,64