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Description

Smer-Barreto, V

Although glucose causes a dose-dependent inhibition of pentose phosphate pathway activity in beta cells, the major pathway for NADPH production, the cytosolic ratio of NADPH/NADP + increases during glucose-stimulated insulin release

Plasma glucose levels were determined by blood glucose sensors (MediSense Optium Xceed) and electrodes (Optium, Abbott Diabetes Care Inc., Alameda, CA)

Biomolecules 10 , 127

Additionally, the reliability of these findings is compromised by the small number of participants and the short duration of the treatments, which lasted only 4 and 8 weeks