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If more than 60% of the meal is retained in the stomach after 2 hours or 10% of the meal is retained after 4 hours, this is indicative of gastroparesis

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So I mean that's from the, from the sort of Alzheimer's side, you wanna make sure that all those surrogate sort of metabolic health markers are important because as I mentioned earlier, one of the earliest features in the disease, even prior to the presentation of clinical symptoms is hypometabolism

Preclinical studies have suggested that these medications may help protect against neurodegenerative diseases such as Alzheimers and Parkinsons