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Clinical trials of semaglutide show that patients using higher doses (1.0 mg or 2.4 mg weekly) achieved 10% to 15% body weight reduction within 6 months, compared to 3% to 5% with placebo

A prespecified analysis of pooled data from the STEP-HFpEF and STEP-HFpEF DM trials demonstrated that significantly more patients treated with Wegovy 2.4 mg SC once weekly had an improvement of at least one in New York Heart Association (NYHA) functional class compared to those who received placebo (32.6% versus 21.5%, respectively

Fluorouracil, carboplatin and cisplatin were purchased from Fujifilm Wako Pure Chemical Corporation and used as received

Tenderness or slight swelling may persist for a day or two, particularly when using larger volumes

The rate constant was 0.0302 per week, corresponding to a 23.0-week half-life