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Indications: Overactive bladder Common symptoms include urgency, urinary incontinence, and increased urinary frequency Side Effects: dry mouth constipation headache urinary tract infection angioedema CNS side effects (confusion, hallucinations, sedation) aggravation of decreased GI motility in patients with GI obstructive disorders Pharmacokinetics: taken orally by extended release tablet, 7.5 or 15 mg once daily metabolized by CYP3A4 & CYP2D6 half life 13-19 hrs Notes: the estimated Walmart cost for generic darifenacin is ~$71 for a supply of 30 generic 15 mg tablets (GoodRx.com

Raw material cost is only one component of total cost

White tomatoes contain carotenoids that absorb UV light which has been linked to the formation of skin cancer

More research will be needed to better understand the biological mechanisms being affected

A 2020 study published in Medical Hypothesis has found that blood clots are common in COVID-19 patients ( 9 )