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This sustains hepatocyte proliferation and advances HCC development ( Collectively, these findings highlight the synergistic harmful impact of alcohol and HBV on liver disease progression, consistent with epidemiological data showing higher HBV marker levels and worse liver outcomes, including cirrhosis and HCC, in alcoholic individuals with HBV infection

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Conservative Titration (Community Approach) Some community members prefer an even more gradual approach, starting at 1mg weekly before moving to the trial-based 2mg starting dose

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