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According to the notification published on 8 Nov 2023, the United States Food and Drug Administration (US-FDA) has authorized Tirzepatide injection, marking a milestone in the realm of chronic weight management for adults grappling with obesity or overweight

For study designs interrogating glucagon dynamics or gastric transit endpoints, the additive rather than redundant action across the two receptor arms is the point of methodological interest

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The FDA has approved these agents for type 2 diabetes management (not type 1 diabetes or diabetic ketoacidosis), with select formulations also approved for chronic weight management in adults with obesity or overweight with weight-related comorbidities