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Supplements that fail these screens (berberine, high-dose NAC, St

Previous studies have found a close relationship between human gut microbes and UC, and may be the most important measure of UC for clinical judgment

Endocrinology and Metabolism Clinics 2013;42(4):869-98 [PubMed: 24286954] 88

However, a 2024 umbrella review concluded that while antioxidant supplements appear safe and well-tolerated, no single supplement can yet be definitively recommended based on current evidence alone, and more large-scale RCTs are needed

These findings collectively emphasize the pivotal role of the NF-B/EAAT3 axis in managing antioxidant stress and influencing lung cancer development