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After we eat, GLP-1 (made in our intestines) helps signal fullness, slows the rate at which food leaves the stomach, and coordinates insulin and glucagon release to keep blood sugar levels in check

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Nevertheless, given the well-recognized expression of the GLP-1 receptor (GLP-1R) in the vasculature, GLP-1RAs are also believed to exert vascular actions that contribute to their cardiorenal benefits, independent of their systemic metabolic and antiinflammatory effects (10, 11)

doi: 10.1038/s41419-021-04184-8 50 HardieD