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Immortalized cell lines are popular tools to study drug hepatotoxicity because they are cost effective, readily available as cryopreserved cells, can be of human origin and generally show robust proliferation

Abed SS, Fitzpatrick SG, Bhattacharyya I, Islam MN, Cohen DM

The new methods have to be not only effective in removal of pharmaceuticals (and their metabolites) but also apply relatively low toxic chemicals and, what is not less important, they should be acceptable from the economic point of view

Treatments might include injections or high-dose oral supplements to restore B12 levels

He specifically warned that LPS contamination can be cumulative it is not that one injection causes a reaction, but the inflammatory load builds until a tipping point is reached