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In a mouse model of allergic rhinitis, it exerts anti-allergic effects by suppressing the Th2 response, thereby reducing IgE and histamine levels, inhibiting the TLR4/MyD88/NF-B pathway to attenuate inflammation, and promoting Th1 activation while restoring the Th1/Th2 immune balance ( 2.2 Alkaloids and polyphenols Following flavonoids, alkaloids and polyphenols represent another class of natural products with significant potential for treating neuroinflammation and allergies via the nasal route

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The most common are mild nausea, bloating, or fatigue early on, but these often fade as your body adjusts