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Despite impaired glucose and pyruvate oxidation, AGC1 deficit does not preclude OXPHOS capacity when alternative substrates are available, supporting a metabolic reprogramming that may ultimately sustain the vital functions of AGC1-deficient NPs [36]

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In fact, overdosing on L-Carnitine may lead to unwanted side effects such as stomach discomfort, nausea, or diarrhea

The cationic amino acid transporter-2 (CAT-2) mediates arginine uptake, which is required for arginase activity and subsequent collagen production, particularly in macrophages [74]

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