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This decline is associated with many classic signs of aging: decreased muscle mass, increased body fat (especially around the abdomen), slower recovery, reduced skin elasticity, and, notably, a significant drop in energy levels

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At 12 months, the on-medication MDS-UPDRS Part III score was 14.9 in the lixisenatide group versus 18.8 in the placebo group, a between-group difference of 3.08 points (P = 0.007) [3]

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