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A 2025 review in Frontiers in Aging characterized this decline as one of the most consistent endocrine signatures of biological aging (Fernandez-Garza et al., 2025

Specifications First available: 07/2020 Shipping weight: 0.27 lb Product code: NOW-08062 UPC: 733739080622 Package quantity: 2 fl oz Dimensions: 5.5 x 1.6 x 1.6 in , 0.27 lb Suggested use Other ingredients Warnings For external use only

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They help the nervous system transition from the on alert state of the sympathetic nervous system to the calming, restorative state of the parasympathetic system