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A 2023 meta-analysis of GLP-1 trial data found retinopathy worsening in approximately 3-5% of participants with pre-existing diabetic eye disease

Smith GL, Smith BD, Buchholz TA, Liao Z, Jeter M, Swisher SG, Hofstetter WL , Ajani JA, McAleer MF, Komaki R, Cox JD

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The metabolism of lipophilic nutrients follows a different absorption pathway through the membrane compared to polar nutrients, majorly due to the non-polarity of lipophilic compounds (94)