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Gln depletion therapy can inhibit Gln metabolism in tumor cells, but in colon cancer, it has been observed that Gln depletion promotes the expression of the aspartate/glutamate transporter SLC1A3 in tumor cells, increasing the intracellular glutamate concentration and promotes Gln synthesis

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The incretin hormone, glucagon-like peptide-1 (GLP-1), has therapeutic potential for the treatment of type 2 diabetes in cirrhotic patients

They employ Trx more effectively than GSH to decrease H 2 O 2 and organic peroxides

When glutathione is deficient, the negative feedback loop is dysregulated allowing for more cysteine to be joined in the production of more glutathione