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A significant decrease in plasma total glutathione (tGSH) reported in four studies from the one research group in children with autistic disorder compared to controls [4648, 50] have been confirmed by another two research groups with respect to autistic disorder [81, 82] as well as study of low functioning children with autism spectrum disorders [85] (Figure 7)

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Thus, deciding on a clear definition of siLNs, investigating when to conduct the FNA, and ultimately concluding a uniform consensus are necessary