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Clinical guidelines generally identify candidates for GLP-1 therapy based on the following profiles: Clinical Obesity: Adults with a Body Mass Index (BMI) of 30 or greater
Safety, Eligibility, and Provider Decision-Making Framework GLP-1 medications carry absolute and relative contraindications, including personal or family history of medullary thyroid cancer, multiple endocrine neoplasia syndrome type 2, and severe renal or hepatic impairment
This study systematically explored the associations between GLP-1RAs and 12 common psychiatric and neurodevelopmental conditions using large-scale GWAS datasets, revealing protective effects against schizophrenia, anxiety disorders, bipolar disorder, bulimia nervosa, PTSD, and autism, with consistent findings across multiple databases for anxiety disorders, autism, and schizophrenia
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