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From the obtained appearance curves the minimum value of collision energy at which a specific fragment can be generated are extrapolated and can be used as proxies of the actual thermodynamic parameter (G form ) which describes the ease of formation of a given species and its stability towards decomposition

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For each study included in the present review, the following data were extracted: Author name, year of study, study site, study design, clinical trial no., inclusion criteria, sample size, characteristics of participants, intervention group ( n ), control group ( n ), primary and secondary outcomes, main results and conclusion of study

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