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Attempts to increase exposure to UA have been made previously in the context of ischaemic stroke, one study finding that fewer patients underwent early ischaemic worsening after intravenous UA administration 54

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They are FDA approved for BMI of 30+, or 27-29.9 if you also have a weight-related medical condition (sleep apnea, hypertension, pre-diabetes, type 2 diabetes, PCOS, others)

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