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Data on demographics, vascular risk factors, and migraine history were collected using a standardized protocol
Oncotarget 6:1107411086 Editor information Editors and Affiliations Rights and permissions Copyright information 2022 Springer Nature Singapore Pte Ltd
Unlike traditional medications such as disulfiram, naltrexone, and buprenorphine, which primarily target neurotransmitter pathways directly associated with addiction, GLP-1RAs modulate reward mechanisms indirectly through metabolic and neuroendocrine pathways
Moreover, metabolomic analyses of serum from patients with severe depression suggest that L-Car and ALCAR may serve as potential biomarkers for this condition (Nie et al., 2021)