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10.1016/j.nbd.2010.05.030 125

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Muscle mass decreases at an accelerating rate, a process called sarcopenia, and since muscle tissue burns more calories than fat tissue, this compounds the metabolic slowdown

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Following, it is not possible to distinguish the rationale for medication initiationsuch as whether initial SGLT2i or GLP-1 RA prescriptions were for weight loss, glycemic control, or cardiovascular protection in this populationwhich may introduce uncertainty in understanding usage patterns

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