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The candidate previously demonstrated promising weight loss outcomes in Phase 2 trials, and its progression into late-stage testing underscores the competitive momentum building in this high-growth therapeutic category In January 2024, Zealand Pharma and Boehringer Ingelheim announced positive Phase 2 results for BI 456906, a long-acting GLP-1/glucagon dual agonist, in obese individuals

According to a previous study, the mice models of UC and CD demonstrate that the colons up-regulation of GPx2 gene expression and down-regulation of aquaporin 8, which facilitates H 2 O 2 diffusion, may protect against severe oxidative stress in IBD (162)

J Diabetes Investig (2015) 6(5):495507

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