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Evidence suggests that antioxidant supplementation to aged horses may reduce inflammatory markers following transportation stress (Miller et al., 2021) and help prevent seasonal immune disruptions (Kdzierski et al., 2020), highlighting a potential link between antioxidant strategies and inflammation management

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While the regulation of alpha-cell GLP-1 production remains poorly understood, several studies have demonstrated that experimentally induced islet stress (e.g., by a cytokine cocktail (60), streptozotocin (STZ) (51), palmitate (61), or chronic hyperglycemia (59)) potently stimulates alpha-cell GLP-1 production

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