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In the pancreas, GLP-1 receptor activation increases glucose-dependent insulin release and decreases glucagon secretion, facilitating glucose homeostasis [18, 38, 39]

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Surgical correction of cleft lip is usually performed in infancy to restore the normal anatomy and functionality of the affected structures, as well as to enhance the psychological and social well-being of both the patient and their family

Specifically, EGF has been implicated in stimulating spermatogenesis and reducing germ cell apoptosis [101], while TGF-1 downregulates pro-inflammatory cytokines such as IL-1 [102]

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