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Over a 3-year follow-up, the SURMOUNT-1 trial found that treatment with tirzepatide (a dual GLP1/GIP agonist) of patients with obesity and prediabetes led to substantial and sustained weight reduction, with a lower risk of progression to type 2 diabetes

The combination of reduced acid production, slowed gastric emptying, and decreased abdominal pressure creates a protective barrier against reflux that strengthens as treatment progresses

Natural active ingredients with potential inhibiting ferroptosis, including traditional Chinese medicine, and their corresponding targets, are also evaluated from the perspective of natural product chemistry and molecular pharmacology

Current perspective regarding the immunopathogenesis of drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (DIHS/DRESS)