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Persistent synovitis can induce VEGF production, promoting neovascularization and increased vascular permeability (143), which may facilitate the influx of iron into the joint cavity and subchondral bone and recruit additional immune cells, thereby intensifying local oxidative stress and inflammatory cascades (144)

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Its dependent on what ingredients the formula contains

9 BPC-157 modulates the Src-Caveolin-1-eNOS pathway, promoting nitric oxide production and vasodilation, which are essential for vascular health and angiogenesis