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The up-regulation of these genes contributed to an enhanced adaptation to high temperature stress in cucumber roots

The observed injuries in the lungs, heart, kidneys, and brain share a common mechanistic hallmark: glycocalyx shedding, increased vascular permeability, neutrophil adhesion, and oxidative stress [5, 17, 21, 104]

Moreover, IGF-1 LR3s ability to modulate glucose metabolismby restricting glucose transport into cellsencourages the use of fat as an energy source, facilitating significant fat loss

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It has been reported that the dysbiosis of the gut microbiota contributed to the occurrence of GLP-1 resistance in T2D mice