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This aligns with the body-first PD subtype theory, suggesting that peripheral initiation may precede CNS involvement (Goedert et al., 2017

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It confirmed our inference: when the expression of GSH was inhibited, GSH would be supplemented through GSHGSSG cycle by up-regulating GR

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The biggest gaps: tesamorelin is the only one with FDA approval and Phase III data showing visceral fat reduction