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The oral capsule format has no published pharmacokinetic, safety, or efficacy data in any species
The highest ALT elevation was greater than 500 which is approximately 10 times the upper limit of normal
Results maintenance demands ongoing use or periodic intensive cycles - stopping treatment initiates gradual regression over 2-6 months as new collagen formation ceases and natural degradation continues
Oral methionine compared with intravenous N-acetyl cysteine for paracetamol overdose"
This means many patients face a choice between indefinite medication use with its ongoing financial costs and health considerations, or accepting that some or most weight may return after discontinuation
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