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In contrast to classical forms of cell death such as necrosis and apoptosis, ferroptosis is distinguished by its lack of cell membrane rupture or swelling, and it does not cause cellular shrinkage, pyknosis, nuclear fragmentation, or the formation of apoptotic bodies

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An aged hippocampus can improve its performance either by temporarily revving up acute repair mechanisms or by settling into a durable, low-growth, low-stress metabolic state

This includes genes involved in collagen synthesis, antioxidant defense, DNA repair, stem cell function, and inflammation