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Diabetologia 68 , 16661673 (2025)

Inflammatory cytokines in ovarian cancer cells, including tumor necrosis factor- (TNF-) and interleukin-1 (IL-1), promote malignant progressionsuch as tumor cell migration and invasionby upregulating the expression of vascular cell adhesion molecule-1 (VCAM-1) and ICAM-1 [79,80,81,82]

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However, semaglutide is contraindicated in individuals with a personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia type 2 (MEN2)