Protein expression and purification Previously described protocols were used to recombinantly express and purify human SHMT1 and SHMT2 76 , human KYAT1 and mouse Kyat3 77 , human PSAT1 78 , mouse Thnsl2 79 and Oat 80
& Sattely, E
Folia Neuropathol 57(2):146160 Bezzi P, Domercq M, Brambilla L, Galli R, Schols D, De Clercq E, Vescovi A, Bagetta G, Kollias G, Meldolesi J, Volterra A (2001) CXCR4-activated astrocyte glutamate release via TNF: amplification by microglia triggers neurotoxicity
The reported symptoms progressively diminished, with psychotic symptoms resolving first, followed by self-reported improvements in mood and cognitive function
This side effect did not persist by day 28 of the trial, and the authors said there was no significant difference in the heart rate or blood pressure between the groups