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Mechanisms of pulmonary endothelial barrier dysfunction in acute lung injury and acute respiratory distress syndrome

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Protocol Quick-Reference Anti-fibrotic therapy for kidney disease (preclinical) Dosing Amount Not standardized (preclinical IV/infusion doses) Frequency Single or chronic infusion (preclinical) Duration Acute to multiple weeks (study-dependent) Administration Route IV Timing KP1 administered as IV bolus in mouse fibrosis models