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While the efficacy data did not survive the Phase IIb primary endpoint, the safety dataset across 900 participants is unusual for a research peptide and is consistently cited as the basis for continued investigational interest

Epithelial-specific Arid1a deletion in mice preserves gland number but reduces FOXA2 and gland-specific genes (Lif, Spink3, Cxcl15), causing implantation and decidualization defects through disrupted LIF-STAT3-EGR1 signaling

Medications and sulfur burps Sulfur burps are sometimes a side effect of GLP-1 receptors (weight loss medications like Ozempic, Mounjaro, and Wegovy)

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