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Never adjust your dose without medical guidance, as proper titration is essential for both efficacy and tolerability of treatment

Monitoring: Schedule comprehensive blood work at month 6 and month 12

Moreover, in another study, L-theanine effectively regulated the secretion of cytokines such as IFN-, IL-2, IL-4, IL-10, IL-12, and TNF- except for IL-6 by activating the mRNA and protein expression of Ras-related protein Rap-1A (Rap1A), 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR), and farnesyl diphosphate synthase (FDPs) in the mevalonate synthesis pathway of rat splenic lymphocytes (93)

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73 Possibly as a consequence of weight reduction, 64,65 canagliflozin reduced plasma leptin and adiponectin levels which could contribute to a reduction of inflammation and fibrosis