Validation of diacylglycerolacyltransferase I as a novel target for the treatment of obesity and dyslipidemia using a potent and selective small molecule inhibitor
Furthermore, the AS + FeNP treatment resulted in increased levels of key phenolics (dihydrocapsaicin, capsaicin, p-coumaric acid, sinapic acid, p-OH benzoic acid, p-OH benzaldehyde, and ferulic acid) and flavonoid compounds (dihydroquercetin, naringenin, kaempferol, dihydrokaempferol, and quercetin) compared to the AS treatment, thus suggesting that these secondary metabolites likely contribute to the stabilization of cellular structures and membranes, ultimately supporting improved physiological functions and resilience under stress
Phospholipids in fact have the ability to form particles organized in two layers, similar to cell membranes, which can contain within them various active substances capable of passing unharmed through digestive processes
doi: 10.1093/rheumatology/key196 122 AmatMBenjamimCFWilliamsLMPratsNTerricabrasEBeletaJet al
Prather AA, Carroll JE
