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The administration routine, realistic expectations on dose escalation, and the GI side-effect curve all need covering at initiation, ideally with written reinforcement

Most weight gain secondary to antipsychotic use occurs in the first 6 months of therapy, so its important to monitor weight closely and intervene early in a patients treatment

Poisson LM, Munkarah A, Madi H, Datta I, Hensley-Alford S, Tebbe C, et al

When administered, it promotes angiogenesis, the formation of new blood vessels, and enhances the production of growth factors and collagen

Koitabashi N, Kass DA (2012) Reverse remodeling in heart failuremechanisms and therapeutic opportunities