[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Albury C, Strain WD, Brocq SL, et al
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Animal model: Protection and repair of intestinal epithelial physical barrier by IGF-1 LR3 Animal models are closer to the physiological environment in vivo and can comprehensively evaluate the impact of IGF-1 LR3 on the physical barrier of intestinal epithelium
When IGF-1 is expressed in a muscle-restricted, locally acting form, it can sustain myocyte hypertrophy and preserve age-independent regenerative capacity without the systemic pathology associated with whole-body IGF-1 elevation
Positive results: Administering oxytocin intranasally improves social abilities, and children with the lowest levels of oxytocin in their blood benefit the most, according to a small clinical trial with 32 autistic participants